| Brian Cox | Ward Abbott |
| Roger Frost | Apfel |
| Matt Damon | Jason Bourne |
| Chris Cooper | Conklin |
| Nicky Naude | Castel |
| Clive Owen | The Professor |
| Gabriel Mann | Zorn |
| Anthony Green | Security Chief |
| Elwin 'Chopper' David | Wombosi Bodyguard (as Elvin 'Chopper' David) |
| Emanuel Booz | Taxi Driver (as Manu Booz) |
| Denis Braccini | Picot |
| Gwenaël Clause | Deauvage |
| Demetri Goritsas | Com Tech |
| Eric Moreau | Policeman (uncredited) |
| David Gasman | Deputy DCM |
| Franka Potente | Marie |
| Adewale Akinnuoye-Agbaje | Wombosi |
| Walton Goggins | Research Tech |
| Josh Hamilton | Research Tech |
| Julia Stiles | Nicolette |
| Orso Maria Guerrini | Giancarlo (as Orso Maria-Guerrini) |
| Tim Dutton | Eamon |
| David Selburg | Marshall |
| Russell Levy | Manheim (as Russel Levy) |
| Hubert Saint-Macary | Morgue Boss (as Hubert Saint Macary) |
| David Bamber | Consulate Clerk |
| Philippe Durand | Morgue Attendant |
| Vincent Franklin | Rawlins |
| Paulette Frantz | Concierge |
| Thierry René | Wombosi Counselor (as Thierry Ashanti) |
| Harry Gilbert | Alain |
| Delphine Lanson | Alliance Secretary |
| William Cagnard | Davies |
| Kait Tenison | Bank Receptionist (as Kait Denison) |
| Joseph Beddelin | Zurich Cop |
| Rainer Werner | Zurich Cop |
| Katie Thynne | Claudia |
| Aaron Lilly | Marine |
| Ronald Benefield | Marine |
| Bradley J. Goode | Marine |
| Troy Lenhardt | Marine |
| Joshua McNew | Marine |
| Joe Montana | Marine |
| John Pawlikowski | Marine |
| Michael Rix | Marine |
| Brad Rizer | Marine |
| Andrew Webster | Marine |
| Houston Williams | Marine |
| Alain Grellier | Salvi |
| Arnaud Henriet | Wombosi Bodyguard |
| Jean-Yves Bilien | Wombosi Bodyguard (as Jean-Yves Billien) |
| Daniel Kobby Erskine | Wombosi Bodyguard (as Daniel Erskine Nartay) |
| Roberto Bestazzoni | Fisherman (uncredited) |
| Ludovic Boulnois | Passer-by in Train Station (uncredited) |
| Jimmy Jean-Louis | Wombosi Bodyguard (uncredited) |
